Radiographic Evaluation of Pathological Bone Lesions: Current Spectrum of Disease and Approach to Diagnosis
Authors
Domb BG, Tyler W, Ellis S, McCarthy E
PMID: 15691112
Purpose
To review the radiographic evaluation of bone lesions and propose a systematic approach to diagnosing pathological bone abnormalities.
Methods
This review outlines a stepwise diagnostic algorithm incorporating radiographic features, clinical history, and lesion characteristics such as location, margin, matrix, and periosteal reaction.
Key Findings
- Radiographs remain the initial and often most important tool in identifying and characterizing bone lesions.
- A structured approach using specific imaging patterns can significantly narrow the differential diagnosis.
- Understanding the biology of benign vs malignant lesions is critical in guiding further imaging and biopsy.
Conclusion
Radiographic assessment, when interpreted systematically, enables accurate early diagnosis of bone lesions and helps determine the need for advanced imaging or biopsy.
What This Means for Patients
A structured radiographic approach improves diagnostic accuracy and may reduce unnecessary procedures for patients with suspicious bone lesions.